IUPAC Name :

N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine;hydrochloride

CAS Number :   56296-78-7

Structural Formula :

Molecular Weight :  78  g/mol

Molecular Formula :   C₁₇H₁₉ClF₃NO

Features of the API:

• Highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
• Manufactured in an USFDA, WHO GMP, ISO 9001, OHSAS 18001 approved site.
• Available in standard pack size of 25 Kgs Net packed in HDPE Carbouys.

Mechanism of Action :

• Fluoxetine has been shown to selectively inhibit the reuptake of serotonin (5-HT) at the presynaptic neuronal membrane.
• Fluoxetine elicits antidepressant effect by inhibiting serotonin re-uptake in the synapse by binding to the re-uptake pump on the neuronal membrane to increase its availability and enhance neurotransmission.
• Fluoxetine-induced inhibition of serotonin reuptake causes increased synaptic concentrations of serotonin in the CNS, resulting in numerous functional changes associated with enhanced serotonergic neurotransmission.