- Cadila Pharmaceuticals Ltd. is one of the largest privately-held pharmaceutical companies in India. Over the past six decades, we have been developing and manufacturing affordable medicines for patients around the world.
- Our innovation-led drug discovery processes ensure the health and well-being of people around the world. Our enhanced investment in innovation and a strong track record in research and development have produced medical miracles that have changed lives and made a profound impact on real life.
- Being a care-focused, research-driven company, we are committed to complying with the highest ethical standard in clinical research and medical practice. We want to be valued not only for our pharmaceutical products but also for the way we conduct our research and business activities.
- We lead our industry in demonstrating the application of cutting-edge research to ethical business practices in producing the alchemy of optimum health outcomes for all.
Sulfolane Overview
Founder Chairman - Indravadan Ambalal Modi, 1926-2012 Chairman- Dr. Rajiv I Modi
Cadila Pharmaceuticals' group company, Casil Health Products Ltd (CHPL), is recognized as the first manufacturer of Sulfolane in India. CHPL operates a dedicated Sulfolane manufacturing facility in Kadi, Gujarat.
Major Applications- Highlighting The Societal Impact
Potential Technology- Reduced dependency on global
player in the area of aromatic/hydrocarbon
extraction e.g. UOP, Shell, Lurgi, Krupp Koppers etc.
New units in hydrocarbon/oil
refineries/pharmaceutical industries will employ
engineers and shift operators hence will create
employment
Removal of benzene from any gasoline blending
stream- Benzene is highly carcinogenic
The technology is devoted for Production of valuable
petrochemicals like Benzene, Toluene, Xylene etc
from refinery or petrochemical feedstock
Business Times The Times of India, February 20 1998
Cadila- first Asian company to export Sulfolane.
Cadila is the third manufacturer of Sulfolane after Shell and Chevron Philips.
Sulfolane -An Indigenous Developed Product
1994 
1996 
1997 
1997- 2015 
2016- 2024 - Cadila Pharmaceuticals- Only plant of its kind in India & Asia.
- Fully indigenous developed technology.
- Offers top-class technology, braving stiff competition
from established multinational giants. - Promote Atma Nirbhar Bharat.
- Dedicated Plant Capacity- 70MT/month
Plant is expandable:
Phase1: 100MT/month
Phase2: 150MT/month- Based on future demand
Cadila is the only manufacturer of Sulfolane in India- can service up major
domestic and export requirement.
SULFOLANE
Also Known as
(Cyclo) Tetramethylene Sulfolane
2,3,4,5-Tetrahydrothiophene-1,1-Dioxide
Thiocyclopentane -1,1-dioxide
Features
An Excellent solvent for many classes of organic compounds and
polymers
Highly polar with outstanding chemical stability
Completely miscible with water
Safe to handle (Very low toxicity)
Availability
Sulfolane Anhydrous (Water, Wt. %, Max.0.25%)
Sulfolane Aqueous (Water, Wt. %, Max.3.0%)
Packing
250 Kgs Net M.S. Drums Tanker load / Small Pack on request.
Main Applications
Aromatic Extraction
- Extraction of Benzene, Toluene, xylene and other
Hydrocarbons from Catalytic reformate and
Pyrolysis naphtha - Production of food Grade Hexane for extraction
of edible oils - Dearomatization of Kerosene for Aviation
Turbine Fuel and Superior Kerosene - Production of gasoline, jet fuels and special
Boiling point (SBP) solvents
Acid Gas Treatment
- Removal of Hydrogen Sulfide, Carbon Dioxide,
Carbon Oxysulfide, Carbon disulfide and
mercaptans from sour gas streams - Recovery of sulfur Dioxide from dilute streams.
Sulfinol process for removal of acid gases utilizes
a mixture of Sulfolane and an amine.
Other Applications
- Fractionation of fatty acidsinto saturated and unsaturated components.
- Separation of lignin from cellulosic materials
- Reaction solvent particularly, for the production of fluoro-aromatics by halogen exchange (HALEX) reaction
- Emulsifier for photographic composition
- Polymerization solvent
- Curing agent for Epoxy resins
- Polymer processing /textiles
- Polymer plasticizer for Cellulose Acetate and polylactams
- Solvent for Electronics and electrical applications.
Extractive Distillation
- Separation of compounds with similar boiling
point e.g. butane and 2-butene,1-prooyl alcohol
and 2-butyl alcohol.
Typical Properties Of Sulfolane-An
| Property | International Specification | Typical Value of CPL Sulfolane-AN | Test Method |
|---|---|---|---|
| Composition,wt% Sulfolane(Waterfree), min. | 99.00 | >99.5 | Gas Chromatography |
| Density at 30 ,g/ml | 1.26-1.27 | 1.26-1.27 | ASTM D 941 |
| Thermal Stability,So2 ppm,max. | 65.00 | <28.0 | IIP Test Procedure |
| Water, wt%,max. | 0.25 | < 0.25 | ASTM D 1744 |
| Ash Content, wt% max. | 0.10 | Traces | ASTM D 482 |
| Distillation(Anhydrous material) %Distilled at 282O C 288o C | 5 (max) 95 (Min) | Nil 100% | ASTM D 1078 |
| Isopropyl Sulfolnyl ether (dry basis) | 0.5% (max) | Traces | Gas Chromatography |
| Sulfolene 02 (dry basis) | 0.2% (min) | Traces | Gas Chromatography |
Typical Properties Of Sulfolane-AQ (W)
| Property | International Specification | Typical Value of CPL Sulfolane-AN | Test Method |
|---|---|---|---|
| Composition,wt% Sulfolane(Waterfree), min. | 99.00 | >99.5 | Gas Chromatography |
| Density at 30 ,g/ml | 1.26-1.27 | 1.26-1.27 | ASTM D 941 |
| Thermal Stability,So2 ppm,max. | 65.00 | <28.0 | IIP Test Procedure |
| Water, wt%,max. | 02.9 | < 2.9 | ASTM D 1744 |
| Ash Content, wt% max. | 0.10 | Traces | ASTM D 482 |
| Distillation(Anhydrous material) %Distilled at 282O C 288o C | 5 (max) 95 (Min) | Nil 100% | ASTM D 1078 |
| Isopropyl Sulfolnyl ether (dry basis) | 0.5% (max) | Traces | Gas Chromatography |
| Sulfolene 02 (dry basis) | 0.2% (min) | Traces | Gas Chromatography |
Sales Contact Details
For inquiries related to Sulfolane, please reach out to:
📧 Email: harpreet.singh@cadilapharma.com
📞 Mobile: +91-9646320777 / +91-7069076614
