Cadila Pharma continues to lead with innovation, advancing global healthcare through world first innovations and a robust research and development (R&D) engine. We drive innovation through our robust research and development capabilities. Its investment in R&D has resulted in breakthrough therapies that continue to transform lives and improve global health outcomes. Our portfolio features several global firsts that demonstrate our dedication to meeting unmet medical needs.
Risorine

Risorine
We set out to improve tuberculosis treatment, where patients often struggled with side effects and low treatment adherence. To change this, we developed Risorine, a first-of-its-kind combination of rifampicin, isoniazid, and piperine, a natural bio-enhancer from black pepper. Piperine increased rifampicin’s absorption, allowing us to lower the dose from 450 mg to 200 mg without reducing effectiveness.
This made the treatment gentler, safer, and easier to continue. Multicentre clinical studies confirmed better cure rates and improved safety, strengthening the fight against tuberculosis.
Rabeloc IV

Rabeloc IV
We saw how critically ill and hospitalised patients often struggled with oral treatment for severe gastric conditions. That’s why we introduced Rabeloc IV, the world’s first intravenous rabeprazole. It offered fast, effective acid control in cases like upper GI bleeding, stress ulcers, reflux, and perioperative care, helping doctors act without delay when oral medication wasn’t an option.
This innovation set a new standard in gastrointestinal care, bringing relief where it was needed most.
Polycap

Polycap
We saw how cardiovascular patients often struggled to keep up with multiple medications. To ease this burden, we created Polycap, a five-in-one fixed-dose combination of Simvastatin, Ramipril, Atenolol, Hydrochlorothiazide, and Aspirin. By bringing everything into a single pill, we improved adherence and simplified daily treatment.
Clinical studies showed meaningful reductions in cardiovascular risk factors, strengthening both prevention and long-term outcomes.
Calcirol AQ

Calcirol AQ
We recognised that traditional oil-based Vitamin D3 injections were often painful, poorly absorbed, and slow to correct deficiency. So, we developed Calcirol AQ, the world’s first aqueous Vitamin D3 injection. Its advanced formulation allows painless delivery, faster absorption, and quicker correction of deficiency.
By replacing oil-based injections, we offered a safer, more effective option for patients who couldn’t tolerate conventional treatment, filling a critical gap in care.
Thrabis

Thrabis
We saw the struggle behind the statistics, where a demanding five-dose rabies regimen often stood in the way of timely care, especially in underserved communities. To overcome this, we introduced Thrabis, a three-dose rabies vaccine given intramuscularly within one week.
By shortening the treatment course, we made vaccination more accessible, improved compliance, and strengthened protection against rabies, particularly in resource-limited settings.
Envas IV

Envas IV
We responded to the urgent needs of critically ill patients, where every moment matters and oral therapy is not an option. To support acute management of hypertension and heart failure in such settings, we developed Envas IV (Enalaprilat Injection), a rapid-onset intravenous ACE inhibitor.
It enables effective blood pressure control in critical care, reduces the risk of heart attack and stroke, and strengthens treatment options for physicians managing high-risk patients.
Sepsivac

Sepsivac
We witnessed how sepsis continued to claim lives despite antibiotic treatment, leaving clinicians with limited options. To respond to this critical need, we developed Sepsivac, an immunomodulatory drug derived from heat-killed Mycobacterium w. By regulating the body’s immune response, Sepsivac improved survival in patients with gram-negative sepsis and demonstrated efficacy in critically ill COVID-19 patients.
This breakthrough marked our role as pioneers in immunotherapy for life-threatening infections.
Mycidac C

Mycidac C
We are committed to advancing cancer care through research-driven innovation. One such breakthrough is India’s first indigenously developed immunotherapy for a specific subtype of lung cancer, Desmocollin-3 (DSC3) expressing squamous non-small cell lung cancer (NSCLC). Powered by heat-killed Mycobacterium w, this therapy works by guiding the body’s own immune system to respond more effectively.
It modulates the tumour microenvironment, strengthens T-cell activity, and reduces immune suppression, offering renewed hope to patients with limited treatment options.
Cadiflu Tetra

Cadiflu Tetra
We set out to strengthen protection against seasonal influenza, a disease that continues to impact millions every year. Conventional egg-based vaccines had their limits, including variable efficacy and allergy concerns. In response, we developed Cadiflu Tetra, India’s first VLP-based quadrivalent influenza vaccine, using WHO-recommended strains to protect against seasonal influenza (flu)—an acute viral respiratory tract infection caused by the influenza virus.
Powered by advanced Virus-Like Particle (VLP) technology, it delivers a strong immune response with an excellent safety profile, while remaining economical and accessible. Cadiflu Tetra is indicated for active immunisation in adults and children from 6 months of age (especially those with respiratory illness or other NCDs), healthcare professionals, and immunocompromised individuals. Protection is achieved with a single 0.5 ml intramuscular injection, making Cadiflu Tetra a convenient and innovative solution for seasonal flu prevention in India.
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